Evans and Hojlund start for United
Erik ten Hag makes three changes to the team that started away at Bayern Munich in midweek.
The most surprising comes in defence where Lisandro Martinez is replaced not by Raphael Varane but by Jonny Evans, who makes his first start for the club since March 2015.
In midfield, 20-year-old Hannibal Mejbri is favoured over Christian Eriksen while Scott McTominay is brought in for Facundo Pellistri.
Bruno Fernandes captains the visitors, and will play in behind forwards Rasmus Hojlund and Marcus Rashford.
Man Utd (4-3-1-2): 24 Onana; 20 Dalot, 2 Lindelof, 35 Evans, 15 Reguilon; 39 McTominay, 18 Casemiro, 46 Mejbri; 8 Fernandes; 11 Hojlund, 10 Rashford
Substitutes: 1 Bayindir, 4 Amrabat, 9 Martial, 14 Eriksen, 17 Garnacho, 19 Varane, 28 Pellistri, 34 Van de Beek, 44 Gore
Source: The Sun